Conantokin-T
Modify Date: 2025-11-10 16:46:30
Conantokin-T structure
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Common Name | Conantokin-T | ||
|---|---|---|---|---|
| CAS Number | 127476-26-0 | Molecular Weight | 2683.81000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C110H175N31O45S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Conantokin-TConantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1]. |
| Name | Conantokin-T |
|---|---|
| Synonym | More Synonyms |
| Description | Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1]. |
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| Related Catalog | |
| Target |
IC50: 2 μM (NMDA)[1] |
| In Vitro | Conantokin-T produces a partial antagonism of NMDA receptor function with an IC50 value of 2 μM[1]. |
| In Vivo | Conantokin-T induces sleep-like symptoms in young mice[1]. |
| Molecular Formula | C110H175N31O45S |
|---|---|
| Molecular Weight | 2683.81000 |
| Exact Mass | 2682.21000 |
| PSA | 1338.87000 |
| LogP | 0.32530 |
| InChIKey | UFVIUSQQHPISRQ-HNJXWIPGSA-N |
| SMILES | CSCCC(NC(=O)C(CCCCN)NC(=O)C(CCC(N)=O)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(C(=O)O)C(=O)O)NC(=O)C(CC(C(=O)O)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CN)C(=O)NC(CC(C)C)C(=O)NC(CC(C(=O)O)C(=O)O)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C(=O)O)C(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(C)C(N)=O)C(C)C |
| Conatokin t |