ACX-362E

Modify Date: 2025-08-25 20:09:18

ACX-362E Structure
ACX-362E structure
 Common Name ACX-362E
CAS Number 1275582-97-2 Molecular Weight 423.30
Density N/A Boiling Point N/A
Molecular Formula C18H20Cl2N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ACX-362E


ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections, with a MIC50 of 2 μg/mL for C. difficile. ACX-362E displays very potent in vitro and in vivo activities against broad spectrum of C. difficile pathogens[1].

 Names

Name ACX-362E

 ACX-362E Biological Activity

Description ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections, with a MIC50 of 2 μg/mL for C. difficile. ACX-362E displays very potent in vitro and in vivo activities against broad spectrum of C. difficile pathogens[1].
Related Catalog
Target

MIC50: 2 μg/mL (C. difficile)[1]

References

[1]. Xu WC, et al. Discovery and development of DNA polymerase IIIC inhibitors to treat Gram-positive infections. Bioorg Med Chem. 2019 Jun 11. pii: S0968-0896(19)30663-7.

 Chemical & Physical Properties

Molecular Formula C18H20Cl2N6O2
Molecular Weight 423.30
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Chemsrc provides ACX-362E(CAS#:1275582-97-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ACX-362E are included as well.>> amp version: ACX-362E

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