dryocrassin ABBA

Modify Date: 2024-01-02 13:51:53

dryocrassin ABBA Structure
dryocrassin ABBA structure
 Common Name dryocrassin ABBA
CAS Number 12777-70-7 Molecular Weight 820.832
Density 1.5±0.1 g/cm3 Boiling Point 1089.0±65.0 °C at 760 mmHg
Molecular Formula C43H48O16 Melting Point N/A
MSDS N/A Flash Point 626.1±30.8 °C

 Use of dryocrassin ABBA


Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities[1][2]. Dryocrassin ABBA exhibits antiviral activity against H5N1 avian influenza virus[1]. Dryocrassin ABBA inhibits the coagulase activity of Staphylococcus aureus vWbp[3]. Dryocrassin ABBA suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival[4].

 Names

Name 2-acetyl-4-[[3-[[3-[(5-acetyl-2,6-dihydroxy-3,3-dimethyl-4-oxocyclohexa-1,5-dien-1-yl)methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
Synonym More Synonyms

 dryocrassin ABBA Biological Activity

Description Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities[1][2]. Dryocrassin ABBA exhibits antiviral activity against H5N1 avian influenza virus[1]. Dryocrassin ABBA inhibits the coagulase activity of Staphylococcus aureus vWbp[3]. Dryocrassin ABBA suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival[4].
Related Catalog
Target

H5N1 avian influenza virus[1]

References

[1]. Ou C, et al. Dryocrassin ABBA, a novel active substance for use against amantadine-resistant H5N1 avian influenza virus. Front Microbiol. 2015 Jun 16;6:592.

[2]. Zhang B, et al. Molecular Mechanism of the Flavonoid Natural Product Dryocrassin ABBA against Staphylococcus aureus Sortase A. Molecules. 2016 Oct 26;21(11).

[3]. Li B, et al. An Inhibitory Effect of Dryocrassin ABBA on Staphylococcus aureus vWbp That Protects Mice From Pneumonia. Front Microbiol. 2019 Jan 23;10:7.

[4]. Fu RH, et al. Dryocrassin suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival. Cell Transplant. 2014;23(4-5):641-56.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 1089.0±65.0 °C at 760 mmHg
Molecular Formula C43H48O16
Molecular Weight 820.832
Flash Point 626.1±30.8 °C
Exact Mass 820.294250
PSA 304.72000
LogP 8.08
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.673

 Synonyms

2,2'-{Methylenebis[(5-butyryl-2,4,6-trihydroxy-3,1-phenylene)methylene]}bis(6-acetyl-3,5-dihydroxy-4,4-dimethyl-2,5-cyclohexadien-1-one)
2,5-Cyclohexadien-1-one,2,2'-(methylenebis((2,4,6-trihydroxy-5-(1-oxobutyl)-3,1-phenylene)methylene)bis(6-acetyl-3,5-dihydroxy
Y0072
4,4'-{Methylenebis[(5-butyryl-2,4,6-trihydroxy-3,1-phenylene)methylene]}bis(2-acetyl-3,5-dihydroxy-6,6-dimethyl-2,4-cyclohexadien-1-one)
2,5-Cyclohexadien-1-one, 2,2'-[methylenebis[[2,4,6-trihydroxy-5-(1-oxobutyl)-3,1-phenylene]methylene]]bis[6-acetyl-3,5-dihydroxy-4,4-dimethyl-
tetraalbaspidin-ABBA
2,4-Cyclohexadien-1-one, 4,4'-[methylenebis[[2,4,6-trihydroxy-5-(1-oxobutyl)-3,1-phenylene]methylene]]bis[2-acetyl-3,5-dihydroxy-6,6-dimethyl-
Dryocrassin ABBA
Dryocrassin
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Chemsrc provides dryocrassin ABBA(CAS#:12777-70-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of dryocrassin ABBA are included as well.>> amp version: dryocrassin ABBA

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