Sipatrigine

Modify Date: 2024-01-05 18:51:25

Sipatrigine Structure
Sipatrigine structure
Common Name Sipatrigine
CAS Number 130800-90-7 Molecular Weight 372.68
Density 1.419 g/cm3 Boiling Point 531.1ºC at 760 mmHg
Molecular Formula C15H16Cl3N5 Melting Point N/A
MSDS N/A Flash Point 275ºC

 Use of Sipatrigine


Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke[1][2].

 Names

Name 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine
Synonym More Synonyms

 Sipatrigine Biological Activity

Description Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke[1][2].
Related Catalog
Target

Sodium channel, calcium channel[1][2].

References

[1]. Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.

[2]. Atticus H. Hainsworth, et al. Sipatrigine (BW 619C89) is a Neuroprotective Agent and a Sodium Channel and Calcium Channel Inhibitor. CNS Drug Reviews. Vol. 6, No. 2, pp. 111-134.

 Chemical & Physical Properties

Density 1.419 g/cm3
Boiling Point 531.1ºC at 760 mmHg
Molecular Formula C15H16Cl3N5
Molecular Weight 372.68
Flash Point 275ºC
Exact Mass 371.04700
PSA 58.28000
LogP 4.02190

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine
Sipatrigine [INN:BAN]
619C89
4-Amino-2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)pyrimidine
Sipatrigine
BW619C89
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: 619C
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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Price: ¥2800/5 mg

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Related Compounds: More...