N-Acetyl mesalazine-d3-1

Modify Date: 2023-04-04 20:23:40

N-Acetyl mesalazine-d3-1 Structure
N-Acetyl mesalazine-d3-1 structure
Common Name N-Acetyl mesalazine-d3-1
CAS Number 1309935-89-4 Molecular Weight 198.19
Density 1.5±0.1 g/cm3 Boiling Point 480.2±40.0 °C at 760 mmHg
Molecular Formula C9H6D3NO4 Melting Point N/A
MSDS N/A Flash Point 244.2±27.3 °C

 Use of N-Acetyl mesalazine-d3-1


N-Acetyl mesalazine-d3-1 is deuterium labeled 5-acetamido-2-hydroxybenzoic acid.

 Names

Name 5-Acetamido-2-hydroxy(2H3)benzoic acid
Synonym More Synonyms

 N-Acetyl mesalazine-d3-1 Biological Activity

Description N-Acetyl mesalazine-d3-1 is deuterium labeled 5-acetamido-2-hydroxybenzoic acid.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 480.2±40.0 °C at 760 mmHg
Molecular Formula C9H6D3NO4
Molecular Weight 198.19
Flash Point 244.2±27.3 °C
Exact Mass 198.071991
LogP 1.48
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.661
Storage condition 2-8°C

 Synonyms

5-Acetamido-2-hydroxy(2H3)benzoic acid
MFCD00463101
Benzoic-2,4,5-d3 acid, 3-(acetylamino)-6-hydroxy-