51-59-2

51-59-2 structure

Name: N-Acetyl Mesalazine
Chemical Name: 5-acetamido-2-hydroxybenzoic acid
CAS Number: 51-59-2
Molecular Formula: C₉H₉NO₄
Molecular Weight: 195.17
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-09-26 19:16:59
Modify Date: 2024-01-10 08:32:42
N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the metabolite of 5-Aminosalicylic Acid (HY-15027) with endoscopic activity. N-Acetyl mesalazine can be used for the research of ulcerative colitis[1].

Name	5-acetamido-2-hydroxybenzoic acid
Synonyms	CJ 46A N-Acetyl Mesalazine 5-Acetamidosalicylic acid N-Acetyl-5-aminosalicylic acid 3-Carboxyparacetamol 5-acetylamino salicylic acid Acetylmesalazine 5-Acetamidosalicylic acid N-Acetyl-5-aminosalicylic acid 5-acetamido-2-hydroxy-benzoic acid

Description	N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the metabolite of 5-Aminosalicylic Acid (HY-15027) with endoscopic activity. N-Acetyl mesalazine can be used for the research of ulcerative colitis[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Allgayer H, et al. Modulation of base hydroxylation by bile acids and salicylates in a model of human colonic mucosal DNA: putative implications in colonic cancer. Dig Dis Sci. 1999 Apr;44(4):761-7. [2]. Fukuda T, et al. Mucosal concentrations of N-acetyl-5-aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine. J Gastroenterol Hepatol. 2020 Nov;35(11):1878-1885.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
HS Code	2924299090

89-57-6

~66%

51-59-2

Literature: DAK-Laboratoriet Patent: US4933330 A1, 1990 ;

89-57-6

108-24-7

~91%

51-59-2

6376-29-0

51-59-2

60-35-5

89-57-6

~82%

51-59-2

96-97-9

89-57-6

51-59-2

Literature: Huebner Justus Liebigs Annalen der Chemie, 1879 , vol. 195, p. 37

69-72-7

51-59-2

Literature: Huebner Justus Liebigs Annalen der Chemie, 1879 , vol. 195, p. 37

3147-53-3

51-59-2

Literature: Grandmougin Chemische Berichte, 1906 , vol. 39, p. 3930

96-97-9

64-19-7

89-57-6

51-59-2

Literature: Huebner Justus Liebigs Annalen der Chemie, 1879 , vol. 195, p. 37

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%