OKI-006

Modify Date: 2024-01-14 14:59:34

OKI-006 Structure
OKI-006 structure
Common Name OKI-006
CAS Number 1315334-23-6 Molecular Weight 482.62
Density N/A Boiling Point N/A
Molecular Formula C21H30N4O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of OKI-006


OKI-006 is a potent and orally active inhibitor of histone deacetylase (HDAC). OKI-006 is a unique congener of the natural product HDAC inhibitor largazole. Histone deacetylases (HDACs) play critical roles in epigenomic regulation, and histone acetylation is dysregulated in many human cancers. OKI-006 has the potential for the research of cancer disease[1].

 Names

Name OKI-006

 OKI-006 Biological Activity

Description OKI-006 is a potent and orally active inhibitor of histone deacetylase (HDAC). OKI-006 is a unique congener of the natural product HDAC inhibitor largazole. Histone deacetylases (HDACs) play critical roles in epigenomic regulation, and histone acetylation is dysregulated in many human cancers. OKI-006 has the potential for the research of cancer disease[1].
Related Catalog
References

[1]. Diamond JR, et al. Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors. Mol Cancer Ther. 2022;21(3):397-406.

 Chemical & Physical Properties

Molecular Formula C21H30N4O5S2
Molecular Weight 482.62