Cyclohexane-PEG1-Br

Modify Date: 2024-01-14 15:49:55

Cyclohexane-PEG1-Br Structure
Cyclohexane-PEG1-Br structure
Common Name Cyclohexane-PEG1-Br
CAS Number 131665-94-6 Molecular Weight 207.10800
Density N/A Boiling Point N/A
Molecular Formula C8H15BrO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cyclohexane-PEG1-Br


Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name (2-bromoethoxy)cyclohexane
Synonym More Synonyms

 Cyclohexane-PEG1-Br Biological Activity

Description Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H15BrO
Molecular Weight 207.10800
Exact Mass 206.03100
PSA 9.23000
LogP 2.73060

 Synonyms

2-bromoethoxy cyclohexane
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