Villocarine A

Modify Date: 2025-08-27 09:20:46

Villocarine A structure	Common Name	Villocarine A
	CAS Number	1319743-81-1	Molecular Weight	366.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₆N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Villocarine A

Villocarine A is a natural vasorelaxant indole alkaloid[1].

Name	Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethylidene-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αE,2S,3E,12bR)-

Description	Villocarine A is a natural vasorelaxant indole alkaloid[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Villocarine A exhibited excellent activity during the initial stage, within 10-30 min after injection, with potent vasorelaxant effects observed at 30 μM against PE-mediated contraction in a rat aorta. Villocarine A exhibited a moderate level of inhibition at 30 μM against PE and 1 μM-induced contraction of the aortic rings in the presence of nicardipine (1 μM) in a Ca2+-free medium[2].
References	[1]. Hirotaka Matsuo, et al. New vasorelaxant indole alkaloids, villocarines A-D from Uncaria villosa. Bioorg Med Chem. 2011 Jul 1;19(13):4075-9. [2]. Faisal Omar, et al. Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective. Molecules. 2021 Apr 15;26(8):2297.

Molecular Formula	C₂₂H₂₆N₂O₃
Molecular Weight	366.45

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Villocarine A
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

Villocarine A suppliers

Villocarine A price