1-Piperazinecarboxylicacid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester

Modify Date: 2024-01-11 08:05:48

1-Piperazinecarboxylicacid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester Structure
1-Piperazinecarboxylicacid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester structure
Common Name 1-Piperazinecarboxylicacid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester
CAS Number 132710-90-8 Molecular Weight 244.33100
Density 1.074g/cm3 Boiling Point 355.8ºC at 760mmHg
Molecular Formula C12H24N2O3 Melting Point 73-77ºC(lit.)
MSDS Chinese USA Flash Point 169ºC
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name tert-butyl 4-(3-hydroxypropyl)piperazine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.074g/cm3
Boiling Point 355.8ºC at 760mmHg
Melting Point 73-77ºC(lit.)
Molecular Formula C12H24N2O3
Molecular Weight 244.33100
Flash Point 169ºC
Exact Mass 244.17900
PSA 53.01000
LogP 0.79730
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.491

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements P261-P301 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Risk Phrases R25
Safety Phrases 26-36/37/39-45
RIDADR UN 2811 6.1/PG 3
Hazard Class 6.1
HS Code 2933599090

 Synthetic Route

~82%

1-Piperazinecarboxylicacid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester Structure

1-Piperazinecar...

CAS#:132710-90-8

Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/134378 A1, 2006 ; Location in patent: Page/Page column 116-117 ; WO 2006/134378 A1

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1-Piperazinecarboxylicacid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester Structure

1-Piperazinecar...

CAS#:132710-90-8

Literature: WO2009/10491 A1, ; Page/Page column 56 ; WO 2009/010491 A1

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1-Piperazinecarboxylicacid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester Structure

1-Piperazinecar...

CAS#:132710-90-8

Literature: US2009/118305 A1, ; US 20090118305 A1

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-[4-(tert-butyloxycarbonyl)-piperazin-1-yl]-propan-1-ol
1-(3-hydroxypropyl)-4-tert-butyloxycarbonylpiperazine
1-Piperazinecarboxylicacid,4-(3-hydroxypropyl)-,1,1-dimethylethyl ester
1-Boc-4-(3-hydroxypropyl)piperazine
1-tert-butoxycarbonyl-4-(3-hydroxypropyl)piperazine
1-(3-hydroxypropyl)-4-tert-butoxycarbonylpiperazine
4-(3-hydroxy-propyl)-piperazine-1-carboxylic acid tert-butyl ester
4-(2-Hydroxypropyl)-1-piperazinecarboxylic acid,1,1-dimethylethyl ester
tert-Butyl-4-(3-hydroxypropyl)piperazine-1-carboxylate
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