PF-10040

Modify Date: 2024-02-04 18:04:17

PF-10040 structure	Common Name	PF-10040
	CAS Number	132928-46-2	Molecular Weight	345.86300
	Density	N/A	Boiling Point	446.3ºC at 760mmHg
	Molecular Formula	C₂₀H₂₄ClNO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	179.9ºC

Use of PF-10040

PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].

Name	1-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydroisoquinoline,hydrochloride
Synonym	More Synonyms

Description	PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Herd CM, et, al. Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits. Br J Pharmacol. 1994 Jan;111(1):7-12. [2]. Wallace JL, et, al. Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF. J Lipid Mediat. 1993 Jun;7(2):183-96.

Description

PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Herd CM, et, al. Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits. Br J Pharmacol. 1994 Jan;111(1):7-12.

[2]. Wallace JL, et, al. Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF. J Lipid Mediat. 1993 Jun;7(2):183-96.

Boiling Point	446.3ºC at 760mmHg
Molecular Formula	C₂₀H₂₄ClNO₂
Molecular Weight	345.86300
Flash Point	179.9ºC
Exact Mass	345.15000
PSA	30.82000
LogP	4.22780
Vapour Pressure	9.68E-08mmHg at 25°C

1-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydroisoquinoline hydrochloride

1-(2-(3,4-Dimethoxyphenyl)ethyl)-3,4-dihydro-6-methylisoquinoline hydrochloride

Isoquinoline,1-(2-(3,4-dimethoxyphenyl)ethyl)-3,4-dihydro-6-methyl-,hydrochloride

1-(3,4-Dimethoxyphenylethyl)-6-methyl-3,4-dihydroisoquinoline

PF-10040

Use of PF-10040

Names

PF-10040 Biological Activity

Chemical & Physical Properties

Synonyms