Domperidone-d6
Modify Date: 2024-01-02 19:18:52
Domperidone-d6 structure
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Common Name | Domperidone-d6 | ||
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| CAS Number | 1329614-18-7 | Molecular Weight | 431.948 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C22H18D6ClN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Domperidone-d6Domperidone-d6 (R33812-d6) is the deuterium labeled Domperidone. Domperidone (R33812) is a selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine[1][2]. |
| Name | 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)(2H6)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one |
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| Synonym | More Synonyms |
| Description | Domperidone-d6 (R33812-d6) is the deuterium labeled Domperidone. Domperidone (R33812) is a selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine[1][2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
[3]. Champion MC, et al. Domperidone, a new dopamine antagonist. CMAJ. 1986;135(5):457-461. |
| Density | 1.3±0.1 g/cm3 |
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| Molecular Formula | C22H18D6ClN5O2 |
| Molecular Weight | 431.948 |
| Exact Mass | 431.199524 |
| LogP | 4.50 |
| Index of Refraction | 1.638 |
| Storage condition | 2-8°C |
| 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl-1,1,2,2,3,3-d6]-4-piperidinyl]-1,3-dihydro- |
| 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)(2H6)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one |
| Domperidone-d6 |