4-O-Methylbutein

Modify Date: 2024-01-03 16:51:47

4-O-Methylbutein Structure
4-O-Methylbutein structure
Common Name 4-O-Methylbutein
CAS Number 13323-67-6 Molecular Weight 286.28
Density 1.4±0.1 g/cm3 Boiling Point 555.6±50.0 °C at 760 mmHg
Molecular Formula C16H14O5 Melting Point 198.5-200.5℃
MSDS N/A Flash Point 210.6±23.6 °C

 Use of 4-O-Methylbutein


4-O-Methylbutein is a phenolic glucoside that can be isolated from Elsholtzia ciliata.4-O-Methylbutein exhibits neuroprotective effects against glutamate-induced HT22 cell death with an EC50 of 35.2 μM[1].

 Names

Name (E)-1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one
Synonym More Synonyms

 4-O-Methylbutein Biological Activity

Description 4-O-Methylbutein is a phenolic glucoside that can be isolated from Elsholtzia ciliata.4-O-Methylbutein exhibits neuroprotective effects against glutamate-induced HT22 cell death with an EC50 of 35.2 μM[1].
Related Catalog
References

[1]. Seo YH, et al. Chemical Constituents from the Aerial Parts of Elsholtzia ciliata and Their Protective Activities on Glutamate-Induced HT22 Cell Death. J Nat Prod. 2020 Oct 23;83(10):3149-3155.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 555.6±50.0 °C at 760 mmHg
Melting Point 198.5-200.5℃
Molecular Formula C16H14O5
Molecular Weight 286.28
Flash Point 210.6±23.6 °C
Exact Mass 286.084137
PSA 86.99000
LogP 2.80
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.684
Storage condition 2-8℃

 Safety Information

Hazard Codes Xn

 Synonyms

(2E)-1-(2,4-Dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-
4-O-Methylbutein
Acrylophenone,2',4'-dihydroxy-3-(m-hydroxy-p-methoxyphenyl)
Chalcone, 2',3,4'-trihydroxy-4-methoxy-
2-PROPEN-1-ONE,1-(2,4-DIHYDROXYPHENYL)-3-(3-HYDROXY-4-METHOXYPHENYL)
Chalcone,2',3,4'-trihydroxy-4-methoxy
1-(2,4-Dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one
3,2',4'-Trihydroxy-4-methoxychalcone
2',3,4'-Trihydroxy-4-methoxy-chalcon
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