BTTAA

Modify Date: 2024-01-06 12:52:26

BTTAA Structure
BTTAA structure
Common Name BTTAA
CAS Number 1334179-85-9 Molecular Weight 430.50700
Density N/A Boiling Point N/A
Molecular Formula C19H30N10O2 Melting Point 115.5 - 116.5 °C
MSDS N/A Flash Point N/A

 Use of BTTAA


BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.

 Names

Name bttaa
Synonym More Synonyms

 BTTAA Biological Activity

Description BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.
Related Catalog
In Vitro BTTAA is a Cu(I)-stabilizing ligand. Using the Glu18AzF mutant of ubiquitin as a model system with C3-Tm3+ and C4-Tm3+, Cu-BTTAA performs significantly better as a catalyst than Cu-THPTA or Cu-TBTA. BTTAA proves to perform much better than THPTA (tris[(1-hydroxy-propyl-1H-1,2,3-triazol-4-yl)methyl]amine) or TBTA (tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine)[1].
References

[1]. Loh CT et al. Lanthanide tags for site-specific ligation to an unnatural amino acid and generation of pseudocontact shifts inproteins. Bioconjug Chem. 2013 Feb 20;24(2):260-8.

 Chemical & Physical Properties

Melting Point 115.5 - 116.5 °C
Molecular Formula C19H30N10O2
Molecular Weight 430.50700
Exact Mass 430.25500
PSA 132.67000
LogP 1.25810
Storage condition 2-8℃

 Synonyms

2-(4-((bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid
2-(4-((bis((1-tert-butyl-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid
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