EGFR-IN-16

Modify Date: 2024-01-14 16:43:41

EGFR-IN-16 Structure
EGFR-IN-16 structure
Common Name EGFR-IN-16
CAS Number 133550-22-8 Molecular Weight 265.26
Density N/A Boiling Point N/A
Molecular Formula C16H11NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EGFR-IN-16


EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].

 Names

Name EGFR-IN-16

 EGFR-IN-16 Biological Activity

Description EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].
Related Catalog
Target

EGFR:4.85 (pIC50)

HER2:4.74 (pIC50)

References

[1]. Kamath S, et al. Receptor-guided alignment-based comparative 3D-QSAR studies of benzylidene malonitrile tyrphostins as EGFR and HER-2 kinase inhibitors. J Med Chem. 2003;46(22):4657-4668.

 Chemical & Physical Properties

Molecular Formula C16H11NO3
Molecular Weight 265.26