3-(4-Bromo-3-chlorophenyl)-1-methoxy-1-methylurea

Modify Date: 2025-08-25 18:25:06

3-(4-Bromo-3-chlorophenyl)-1-methoxy-1-methylurea Structure
3-(4-Bromo-3-chlorophenyl)-1-methoxy-1-methylurea structure
Common Name 3-(4-Bromo-3-chlorophenyl)-1-methoxy-1-methylurea
CAS Number 13360-45-7 Molecular Weight 293.545
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H10BrClN2O2 Melting Point 95-97℃
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name chlorbromuron
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Melting Point 95-97℃
Molecular Formula C9H10BrClN2O2
Molecular Weight 293.545
Exact Mass 291.961395
PSA 41.57000
LogP 3.26
Index of Refraction 1.616
InChIKey NLYNUTMZTCLNOO-UHFFFAOYSA-N
SMILES CON(C)C(=O)Nc1ccc(Br)c(Cl)c1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS2800000
CHEMICAL NAME :
Urea, 3-(4-bromo-3-chlorophenyl)-1-methoxy-1-methyl-
CAS REGISTRY NUMBER :
13360-45-7
LAST UPDATED :
199806
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C9-H10-Br-Cl-N2-O2
MOLECULAR WEIGHT :
293.57
WISWESSER LINE NOTATION :
GR BE EMVN1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
CIGET* Ciba-Geigy Toxicology Data/Indexes. (Ciba-Geigy Corp., 556 Morris Ave., Summit, NJ 07901) Volume(issue)/page/year: -,-,1977 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 37,370,1982
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1050 mg/m3/6H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,137,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,137,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CIGET* Ciba-Geigy Toxicology Data/Indexes. (Ciba-Geigy Corp., 556 Morris Ave., Summit, NJ 07901) Volume(issue)/page/year: -,-,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5400 ug/m3/17W-I
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Cardiac - EKG changes not diagnostic of specified effects Liver - fatty liver degeneration
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(8),76,1981 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1309 mg/kg
SEX/DURATION :
male 11 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(8),76,1981 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3 JAN 1993

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H332
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/38
Safety Phrases S26
RIDADR NONH for all modes of transport
RTECS YS2800000
HS Code 2928000032

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2928000032
Summary 2928000032 3-(4-bromo-3-chlorophenyl)-1-methoxy-1-methylurea。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

 Articles10

More Articles
[On the determination of chlorpropham, metobromuron and chlorbromuron residues in drugs of the 2. AB-DDR (author's transl)].

Pharmazie 37(5) , 370-4, (1982)

A method for analyzing drugs of the 2. AB-DDR for residues of chlorpropham, metobromuron and chlorbromuron is proposed. It is based on the detection of aniline derivatives resulting from alkaline hydr...

[Thin-layer chromatographic testing of drugs of the East German Pharmacopoeia, 2d edition, metobromuron and chlorbromuron residues].

Pharmazie 36(4) , 304, (1981)

[Gas chromatographic determination of chlorpropham, metobromuron and chlorbromuron residues in drugs of the East German Pharmacopoeia, 2d edition].

Pharmazie 36(5) , 386-7, (1981)

 Bioassay

View more

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
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 Synonyms

N’-(4-bromo-3-chlorophenyl)-N-methoxy-N-methylurea
EINECS 236-411-9
3-(4-Bromo-3-chlorophenyl)-1-methoxy-1-methylurea
MFCD00055474
Chlorbromuron
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