Pancreastatin (33-48) (human) trifluoroacetate salt

Modify Date: 2024-01-08 18:09:15

Pancreastatin (33-48) (human) trifluoroacetate salt Structure
Pancreastatin (33-48) (human) trifluoroacetate salt structure
Common Name Pancreastatin (33-48) (human) trifluoroacetate salt
CAS Number 133605-57-9 Molecular Weight 1819.00000
Density N/A Boiling Point N/A
Molecular Formula C78H123N21O27S Melting Point N/A
MSDS USA Flash Point N/A

 Use of Pancreastatin (33-48) (human) trifluoroacetate salt


Pancreastatin (37-52), human is a pancreastatin fragment. Pancreastatin a CgA-derived peptide (CgA residues 250–301) with biological activity, inhibited the releasing of insulin by islet beta cells[1][2].

 Names

Name Chromograinin A fragment 286-301
Synonym More Synonyms

  Biological Activity

Description Pancreastatin (37-52), human is a pancreastatin fragment. Pancreastatin a CgA-derived peptide (CgA residues 250–301) with biological activity, inhibited the releasing of insulin by islet beta cells[1][2].
Related Catalog
References

[1]. Qiao XW, et al. Chromogranin A is a reliable serum diagnostic biomarker for pancreatic neuroendocrine tumors but not for insulinomas. BMC Endocr Disord. 2014 Aug 7;14:64.  

[2]. O'Dorisio TM, et al. Development of a highly sensitive and specific carboxy-terminal human pancreastatin assay to monitor neuroendocrine tumor behavior. Pancreas. 2010 Jul;39(5):611-6.  

 Chemical & Physical Properties

Molecular Formula C78H123N21O27S
Molecular Weight 1819.00000
Exact Mass 1817.86000
PSA 813.61000
LogP 1.76890

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles4

More Articles
The endocrine role for chromogranin A: a prohormone for peptides with regulatory properties.

Cell. Mol. Life Sci. 64 , 2863-2886, (2007)

Chromogranin A (CgA) belongs to the granin family of uniquely acidic secretory proteins co-stored and co-secreted with other hormones and peptides in elements of the diffuse neuroendocrine system. The...

Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin.

Regul. Pept. 161 , 8-14, (2010)

Pancreastatin is one of the regulatory peptides derived from intracellular and/or extracellular processing of chromogranin A, the soluble acidic protein present in the secretory granules of the neuroe...

Effect of chromogranin A (pancreastatin) fragment on invasion of prostate cancer cells.

Cancer Lett. 147 , 207-213, (1999)

We investigated the effect of chromogranin A (pancreastatin) fragment on the invasion of PC-3, DU-145 and LNCaP prostate cancer cells through a reconstituted basement membrane (Matrigel) using a Trans...

 Synonyms

Pancreastatin Fragment 37-52 human
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