Azido-PEG3-phosphonic acid ethyl ester

Modify Date: 2024-01-30 04:37:31

Azido-PEG3-phosphonic acid ethyl ester Structure
Azido-PEG3-phosphonic acid ethyl ester structure
Common Name Azido-PEG3-phosphonic acid ethyl ester
CAS Number 1337527-24-8 Molecular Weight 339.33
Density N/A Boiling Point N/A
Molecular Formula C12H26N3O6P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-phosphonic acid ethyl ester


Azido-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-phosphonic acid ethyl ester

 Azido-PEG3-phosphonic acid ethyl ester Biological Activity

Description Azido-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H26N3O6P
Molecular Weight 339.33
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