(S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester

Modify Date: 2024-01-17 20:17:10

(S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester Structure
(S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester structure
Common Name (S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester
CAS Number 1337529-56-2 Molecular Weight 453.29700
Density N/A Boiling Point N/A
Molecular Formula C18H17F5NO5P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester


Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1].

 Names

Name (S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester
Synonym More Synonyms

  Biological Activity

Description Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1].
Related Catalog
References

[1]. Shi GH, et al. The preparation of Suo Feibuwei. CN109535213A.

 Chemical & Physical Properties

Molecular Formula C18H17F5NO5P
Molecular Weight 453.29700
Exact Mass 453.07600
PSA 83.67000
LogP 5.26860

 Synonyms

.(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
.(S)-isopropyl-2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
.2(S)-[((R)-2,3,4,5,6-pentafluoro-phenoxy)-phenoxy-phosphorylamino]propionic acid isopropyl ester
.(S)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
propan-2-yl (2S)-2-[[(R)-pentafluorophenoxy(phenoxy)phosphoryl]amino]propanoate
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