1337529-56-2
1337529-56-2 structure
- Name: (S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester
- Chemical Name: (S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester
- CAS Number: 1337529-56-2
- Molecular Formula: C18H17F5NO5P
- Molecular Weight: 453.29700
- Catalog: Research Areas Infection
- Create Date: 2016-04-17 09:52:07
- Modify Date: 2024-01-17 20:17:10
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Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1].
| Name | (S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester |
|---|---|
| Synonyms |
.(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
.(S)-isopropyl-2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate .2(S)-[((R)-2,3,4,5,6-pentafluoro-phenoxy)-phenoxy-phosphorylamino]propionic acid isopropyl ester .(S)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate propan-2-yl (2S)-2-[[(R)-pentafluorophenoxy(phenoxy)phosphoryl]amino]propanoate |
| Description | Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Shi GH, et al. The preparation of Suo Feibuwei. CN109535213A. |
| Molecular Formula | C18H17F5NO5P |
|---|---|
| Molecular Weight | 453.29700 |
| Exact Mass | 453.07600 |
| PSA | 83.67000 |
| LogP | 5.26860 |