beta-hydroxyethoxyacetic acid

Modify Date: 2024-01-02 10:46:12

beta-hydroxyethoxyacetic acid Structure
beta-hydroxyethoxyacetic acid structure
Common Name beta-hydroxyethoxyacetic acid
CAS Number 13382-47-3 Molecular Weight 120.10400
Density 1.29g/cm3 Boiling Point 323.8ºC at 760mmHg
Molecular Formula C4H8O4 Melting Point 44ºC
MSDS N/A Flash Point 147.3ºC

 Use of beta-hydroxyethoxyacetic acid


(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine[1].

 Names

Name 2-(2-hydroxyethoxy)acetic acid
Synonym More Synonyms

 beta-hydroxyethoxyacetic acid Biological Activity

Description (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine[1].
Related Catalog
In Vitro (2-Hydroxyethoxy)acetic acid (HEAA) exists in a pH-dependent equilibrium with the cyclic lactone dioxan-2-one, whereby the open-chain form of (2-Hydroxyethoxy)acetic acid is found to be stable under acidic conditions[1].
In Vivo The main metabolic pathway of 1,4-Dioxane is oxidized by cytochrome P450 monooxygenase to (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA), which is then rapidly excreted in urine[1].
References

[1]. Elisabeth Eckert, et al. Reliable quantitation of β-hydroxyethoxyacetic acid in human urine by an isotope-dilution GC-MS procedure. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 15;935:80-4.

 Chemical & Physical Properties

Density 1.29g/cm3
Boiling Point 323.8ºC at 760mmHg
Melting Point 44ºC
Molecular Formula C4H8O4
Molecular Weight 120.10400
Flash Point 147.3ºC
Exact Mass 120.04200
PSA 66.76000
Vapour Pressure 2.01E-05mmHg at 25°C
Index of Refraction 1.458

 Safety Information

HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

(2-hydroxy-ethoxy)-acetic acid
Acetic acid,2-(2-hydroxyethoxy)
(2-Hydroxy-aethoxy)-essigsaeure
Glykoloxyessigsaeure