5-Methyltetrahydrofolate

Modify Date: 2025-08-23 11:46:40

5-Methyltetrahydrofolate Structure
5-Methyltetrahydrofolate structure
Common Name 5-Methyltetrahydrofolate
CAS Number 134-35-0 Molecular Weight 459.46
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C20H25N7O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Methyltetrahydrofolate


5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid[1].

 Names

Name 5-methyltetrahydrofolic acid
Synonym More Synonyms

 5-Methyltetrahydrofolate Biological Activity

Description 5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid[1].
Related Catalog
References

[1]. Wright AJ, et al. Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-week placebo-controlled study in healthy adults. Br J Nutr. 2010 Mar;103(5):724-9.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C20H25N7O6
Molecular Weight 459.46
Exact Mass 459.186646
PSA 180.77000
LogP -2.61
Index of Refraction 1.733
InChIKey ZNOVTXRBGFNYRX-ABLWVSNPSA-N
SMILES CN1c2c(nc(N)[nH]c2=O)NCC1CNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1
Storage condition 2-8℃

 5-MethyltetrahydrofolateBioassay

View more

Name: Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of VER...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4651404
Name: Inhibition of Escherichia coli K-12 recombinant His-tagged folylpoly-gamma-glutamate ...
Source: ChEMBL
Target: Dihydrofolate synthase/folylpolyglutamate synthase
External Id: CHEMBL1227290
Total 2, Current Page 1 of 1
1

 Synonyms

MethylFolate
5-Methyltetrahydropteroylglutamate
5-methyl-tetrahydrofolate
N5-Methyl-tetrahydrofolic acid
N-(5-methyl-5,6,7,8-tetrahydro-pteroyl)-glutamic acid
5-Methyltetrahydrofolate
(+-)-L-5-Methyl-5,6,7,8-tetrahydrofolsaeure
N-(4-{[(2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl)methyl]amino}benzoyl)-D-glutamic acid
n5-methyltetrahydrofolate
methyl-THF
N5-methyl-THF
5-methyl-(6S)-tetrahydrofolic acid
5-methyl-5,6,7,8-tetrahydrofolate
5-METHYL-THF
METHYLTETRAHYDROFOLICACID
methyl-H4F
n5-CH3-THF
N5-Methyl-tetrahydrofolate
N-Methyltetrahydrofolic acid
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.