2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-2-PROPYNYL-, HYDROCHLORIDE

Modify Date: 2024-07-17 23:13:17

2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-2-PROPYNYL-, HYDROCHLORIDE Structure
2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-2-PROPYNYL-, HYDROCHLORIDE structure
Common Name 2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-2-PROPYNYL-, HYDROCHLORIDE
CAS Number 134467-58-6 Molecular Weight 221.726
Density N/A Boiling Point N/A
Molecular Formula C13H16ClN Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-2-PROPYNYL-, HYDROCHLORIDE


2-PAT, an analogue of Rasagiline and Selegiline, a reversible MAO-A inhibitor with an IC50 of 0.721 µM. 2-PAT is an inactivator of MAO-B with an IC50 of 14.6 µM. 2-PAT has the potential for Parkinson’s disease and depression research[1].

 Names

Name N-(2-Propyn-1-yl)-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (1:1)
Synonym More Synonyms

  Biological Activity

Description 2-PAT, an analogue of Rasagiline and Selegiline, a reversible MAO-A inhibitor with an IC50 of 0.721 µM. 2-PAT is an inactivator of MAO-B with an IC50 of 14.6 µM. 2-PAT has the potential for Parkinson’s disease and depression research[1].
Related Catalog
Target

MAO-A:0.721 μM (IC50)

MAO-B:14.6 μM (IC50)

References

[1]. Letitia Meiring, et al. The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase. Bioorg Med Chem Lett. 2022 Jul 1;67:128746.

 Chemical & Physical Properties

Molecular Formula C13H16ClN
Molecular Weight 221.726
Exact Mass 221.097122

 Synonyms

N-(2-Propyn-1-yl)-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (1:1)
MFCD09998861
2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propyn-1-yl-, hydrochloride (1:1)
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