Nefopam D3 hydrochloride

Modify Date: 2024-01-17 19:30:48

Nefopam D3 hydrochloride structure	Common Name	Nefopam D3 hydrochloride
	CAS Number	1346603-30-2	Molecular Weight	292.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₇D₃ClNO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Nefopam D3 hydrochloride

Nefopam D3 hydrochloride is the deuterium labeled Nefopam hydrochloride. Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo[1][2].

Name	Nefopam D3 hydrochloride

Description	Nefopam D3 hydrochloride is the deuterium labeled Nefopam hydrochloride. Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo[1][2].
Related Catalog	Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kim KH, et al. Rediscovery of nefopam for the treatment of neuropathic pain. Korean J Pain. 2014 Apr;27(2):103-11. [3]. Baht GS, et al. Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. Bone. 2017 May;98:31-36. [4]. Poon R, et al. A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. PLoS One. 2012;7(5):e37940.

Molecular Formula	C₁₇H₁₇D₃ClNO
Molecular Weight	292.82

Nefopam D3 hydrochloride

Use of Nefopam D3 hydrochloride

Names

Nefopam D3 hydrochloride Biological Activity

Chemical & Physical Properties