Propafenone-d5 (hydrochloride)

Modify Date: 2024-01-12 20:15:41

Propafenone-d5 (hydrochloride) Structure
Propafenone-d5 (hydrochloride) structure
Common Name Propafenone-d5 (hydrochloride)
CAS Number 1346605-05-7 Molecular Weight 382.936
Density N/A Boiling Point N/A
Molecular Formula C21H23D5ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propafenone-d5 (hydrochloride)


Propafenone D5 (SA-79 D5) hydrochloride is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79) hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].

 Names

Name 1-(2-{[2-Hydroxy-3-(propylamino)(2H5)propyl]oxy}phenyl)-3-phenyl-1-propanone hydrochloride (1:1)
Synonym More Synonyms

 Propafenone-d5 (hydrochloride) Biological Activity

Description Propafenone D5 (SA-79 D5) hydrochloride is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79) hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Cox L, et al. Levomepromazine for nausea and vomiting in palliative care. Cochrane Database Syst Rev. 2015;2015(11):CD009420. Published 2015 Nov 2.

[2]. http://en.wikipedia.org/wiki/Propafenone

 Chemical & Physical Properties

Molecular Formula C21H23D5ClNO3
Molecular Weight 382.936
Exact Mass 382.207153

 Synonyms

1-Propanone, 1-[2-[[2-hydroxy-3-(propylamino)propyl-1,1,2,3,3-d5]oxy]phenyl]-3-phenyl-, hydrochloride (1:1)
1-(2-{[2-Hydroxy-3-(propylamino)(2H5)propyl]oxy}phenyl)-3-phenyl-1-propanone hydrochloride (1:1)