LAS190792

Modify Date: 2025-08-26 19:08:39

LAS190792 structure	Common Name	LAS190792
	CAS Number	1347232-69-2	Molecular Weight	811.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₉H₄₃ClN₄O₉S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LAS190792

LAS190792 (AZD8999) is a potent muscarinic antagonist and β2-adrenoceptor agonist with pIC50 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6 for M1, M2, M3, M4, M5, β1, β2, β3, respectively. LAS190792 can be used as a bronchodilatorsup>[1].

Name	LAS190792

Description	LAS190792 (AZD8999) is a potent muscarinic antagonist and β2-adrenoceptor agonist with pIC50 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6 for M1, M2, M3, M4, M5, β1, β2, β3, respectively. LAS190792 can be used as a bronchodilatorsup>[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	β1 adrenoceptor:7.5 (pIC50) β2 adrenoceptor:9.1 (pIC50) β3 adrenoceptor:5.6 (pIC50) mAChR1:8.9 (pIC50) mAChR2:8.8 (pIC50) mAChR3:8.8 (pIC50) mAChR4:9.2 (pIC50) mAChR5:8.2 (pIC50)
References	[1]. Aparici M, et al. Pharmacological preclinical characterization of LAS190792, a novel inhaled bifunctional muscarinic receptor antagonist /β2-adrenoceptor agonist (MABA) molecule. Pulm Pharmacol Ther. 2017 Oct;46:1-10.

Molecular Formula	C₃₉H₄₃ClN₄O₉S₂
Molecular Weight	811.36
InChIKey	SNXJYSXRLKUBSZ-DKVSQIIISA-N
SMILES	COc1cc(NC(=O)OCCN(C)C2CCC(OC(=O)C(O)(c3cccs3)c3cccs3)CC2)c(Cl)cc1CNCC(O)c1ccc(O)c2[nH]c(=O)ccc12

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LAS190792
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: LAS190792
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.