ETI

Modify Date: 2026-07-07 18:22:52

ETI Structure
ETI structure
Common Name ETI
CAS Number 13488-22-7 Molecular Weight 300.44
Density 1.0±0.1 g/cm3 Boiling Point 473.8±40.0 °C at 760 mmHg
Molecular Formula C20H28O2 Melting Point N/A
MSDS Chinese USA Flash Point 221.9±22.0 °C

 Use of ETI


5,8,11-Eicosatriynoic acid (ETI) is a lipoxygenase inhibitor that blocks LTC4 biosynthesis in mast cell tumor cells[1].

 Names

Name 5,8,11-icosatriynoic acid
Synonym More Synonyms

 ETI Biological Activity

Description 5,8,11-Eicosatriynoic acid (ETI) is a lipoxygenase inhibitor that blocks LTC4 biosynthesis in mast cell tumor cells[1].
Related Catalog
References

[1]. L Orning, et al. Inhibition of leukotriene C and leukotriene D biosynthesis. J Biol Chem. 1980 Sep 10;255(17):8023-6.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 473.8±40.0 °C at 760 mmHg
Molecular Formula C20H28O2
Molecular Weight 300.44
Flash Point 221.9±22.0 °C
Exact Mass 300.208923
PSA 37.30000
LogP 6.15
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.507
InChIKey OWYNLPMPYBYKJP-UHFFFAOYSA-N
SMILES CCCCCCCCC#CCC#CCC#CCCCC(=O)O

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 2916190090

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Articles26

More Articles
Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells.

Biochim. Biophys. Acta 1401(3) , 277-88, (1998)

Nonsteroidal anti-inflammatory drugs (NSAIDs) and short-chain fatty acids are effective suppressors of colorectal cancer that may work in part by accentuating apoptosis of transformed cells. Since rea...

Eicosatetraynoic and arachidonic acid-induced changes in cell membrane fluidity consonant with differences in computer-aided design-structures.

Biochim. Biophys. Acta 1105(2) , 285-90, (1992)

ETYA (5,8,11,14-eicosatetraynoic acid), a competitive analogue of arachidonic acid (AA), inhibits the proliferation of U937 (human monoblastoid) and PC3 (human prostate) cancer cells, without the over...

Chlamydia pneumoniae induces nitric oxide synthase and lipoxygenase-dependent production of reactive oxygen species in platelets. Effects on oxidation of low density lipoproteins.

Thromb. Haemost. 94(2) , 327-35, (2005)

There is increasing evidence that Chlamydia pneumoniae is linked to atherosclerosis and thrombosis. In this regard, we have recently shown that C. pneumoniae stimulates platelet aggregation and secret...

 ETIBioassay

View more

Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
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 Synonyms

Icosa-5,8,11-triynoic acid
MFCD00077343
5,8,11-Eicosatriynoic acid
5,8,11-Icosatriynoic acid
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