(+)-Clopidogrel bisulfate

Modify Date: 2024-01-02 12:09:45

(+)-Clopidogrel bisulfate Structure
(+)-Clopidogrel bisulfate structure
Common Name (+)-Clopidogrel bisulfate
CAS Number 135046-48-9 Molecular Weight 419.900
Density N/A Boiling Point 423.7ºC at 760 mmHg
Molecular Formula C16H18ClNO6S2 Melting Point 184ºC
MSDS USA Flash Point 210ºC

 Use of (+)-Clopidogrel bisulfate


Clopidogrel sulfate is an antiplatelet agent. Specifically, Clopidogrel sulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Clopidogrel sulfate can be used for research of heart disease and stroke[1].

 Names

Name (S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
Synonym More Synonyms

 (+)-Clopidogrel bisulfate Biological Activity

Description Clopidogrel sulfate is an antiplatelet agent. Specifically, Clopidogrel sulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Clopidogrel sulfate can be used for research of heart disease and stroke[1].
Related Catalog
References

[1]. Pindelska E, et al. Solid-state NMR as an effective method of polymorphic analysis: solid dosage forms of clopidogrel hydrogensulfate. J Pharm Sci. 2015 Jan;104(1):106-13.  

 Chemical & Physical Properties

Boiling Point 423.7ºC at 760 mmHg
Melting Point 184ºC
Molecular Formula C16H18ClNO6S2
Molecular Weight 419.900
Flash Point 210ºC
Exact Mass 419.026398
PSA 140.76000
LogP 4.03980
Vapour Pressure 8.71E-09mmHg at 25°C
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
HS Code 2934999090

 Synthetic Route

~91%

(+)-Clopidogrel bisulfate Structure

(+)-Clopidogrel...

CAS#:135046-48-9

Literature: RICHTER GEDEON NYRT. Patent: WO2009/77797 A1, 2009 ; Location in patent: Page/Page column 13 ;

~84%

(+)-Clopidogrel bisulfate Structure

(+)-Clopidogrel...

CAS#:135046-48-9

Literature: IPCA Laboratories Limited Patent: EP1772455 A2, 2007 ; Location in patent: Page/Page column 10 ;

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(+)-Clopidogrel bisulfate Structure

(+)-Clopidogrel...

CAS#:135046-48-9

Literature: US2004/24011 A1, ; Page 7 ;

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD00876395
Plavix
Clopidogrel Hydrogen sulfate
Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate (1:1)
Clopidogrel bisulfate
(2S)-(2-chlorophényl)(6,7-dihydrothiéno[3,2-c]pyridin-5(4H)-yl)éthanoate de méthyle sulfate
Clopidogrel Hydrogensulfate
Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)
(+)-Clopidogrel hydrogen sulfate
Clopidogrel bisulphate
(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate (1:1)
a-(S)-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic Acid Methyl Ester Sulfate (1:1)
Methyl aS-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate Sulfate (1:1)
Methyl-(2S)-(2-chlorphenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoatsulfat
S-(+)-Clopidogrel Hydrogen Sulfate
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