T.cruzi-IN-1

Modify Date: 2024-01-30 19:34:50

T.cruzi-IN-1 structure	Common Name	T.cruzi-IN-1
	CAS Number	1350920-22-7	Molecular Weight	390.44200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₅F₃N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of T.cruzi-IN-1

T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease[1].

Name	N-benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide

Description	T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 8 nM (Trypanosoma cruzi)[1]
In Vitro	T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity[1].
References	[1]. Germain AR, et al. Identification of small-molecule inhibitors of Trypansoma cruzi replication. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7197-200.

Molecular Formula	C₂₂H₂₅F₃N₂O
Molecular Weight	390.44200
Exact Mass	390.19200
PSA	23.55000
LogP	4.51390
Storage condition	-20℃

DC Chemicals Limited
China
Product Name: MDK1088（T.cruzi Inhibitor）
Price: $550.0/100mg $990.0/250mg $1980.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-benzyl-N-Methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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