Vactosertib (TEW-7197)

Modify Date: 2024-01-11 18:21:42

Vactosertib (TEW-7197) Structure
Vactosertib (TEW-7197) structure
Common Name Vactosertib (TEW-7197)
CAS Number 1352608-82-2 Molecular Weight 399.424
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C22H18FN7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Vactosertib (TEW-7197)


Vactosertib (EW-7197) is an ATP-competitive inhibitor of ALK5 with an IC50 of 12.9 nM. It also inhibits ALK2 and ALK4 at nanomolar concentrations.

 Names

Name 1H-​Imidazole-​2-​methanamine, N-​(2-​fluorophenyl)​-​5-​(6-​methyl-​2-​pyridinyl)​-​4-​[1,​2,​4]​triazolo[1,​5-​a]​pyridin-​6-​yl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C22H18FN7
Molecular Weight 399.424
Exact Mass 399.160767
PSA 83.79000
LogP 3.19
Index of Refraction 1.725
Storage condition -20℃

 Synonyms

2-Fluoro-N-{[4-(6-methyl-2-pyridinyl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl}aniline
1H-Imidazole-2-methanamine, N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-
EW-7197
N-[[4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline
TEW-7197
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Price: $114/10mM*1mLinDMSO

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