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  • DC Chemicals Limited
  • China
  • Product Name: EW-7197
  • Price: $450.0/100mg $750.0/250mg $1600.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1352608-82-2

1352608-82-2 structure
1352608-82-2 structure
  • Name: Vactosertib (TEW-7197)
  • Chemical Name: 1H-​Imidazole-​2-​methanamine, N-​(2-​fluorophenyl)​-​5-​(6-​methyl-​2-​pyridinyl)​-​4-​[1,​2,​4]​triazolo[1,​5-​a]​pyridin-​6-​yl
  • CAS Number: 1352608-82-2
  • Molecular Formula: C22H18FN7
  • Molecular Weight: 399.424
  • Catalog: Biochemical Inhibitor TGF-beta/Smad signaling pathway inhibitor (TGF-beta/Smad) TGF-beta/Smad inhibitor
  • Create Date: 2018-12-09 14:07:56
  • Modify Date: 2024-01-11 18:21:42
  • Vactosertib (EW-7197) is an ATP-competitive inhibitor of ALK5 with an IC50 of 12.9 nM. It also inhibits ALK2 and ALK4 at nanomolar concentrations.

Name 1H-​Imidazole-​2-​methanamine, N-​(2-​fluorophenyl)​-​5-​(6-​methyl-​2-​pyridinyl)​-​4-​[1,​2,​4]​triazolo[1,​5-​a]​pyridin-​6-​yl
Synonyms 2-Fluoro-N-{[4-(6-methyl-2-pyridinyl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl}aniline
1H-Imidazole-2-methanamine, N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-
EW-7197
N-[[4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline
TEW-7197
Density 1.4±0.1 g/cm3
Molecular Formula C22H18FN7
Molecular Weight 399.424
Exact Mass 399.160767
PSA 83.79000
LogP 3.19
Index of Refraction 1.725
Storage condition -20℃