Protokylol

Modify Date: 2025-08-24 07:25:33

Protokylol structure	Common Name	Protokylol
	CAS Number	136-70-9	Molecular Weight	331.36300
	Density	1.336g/cm3	Boiling Point	585ºC at 760 mmHg
	Molecular Formula	C₁₈H₂₁NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	307.6ºC

Use of Protokylol

Protokylol (Caytine; JB-251) is a beta-adrenergic receptor agonist and TRPV1 agonist. Protokylol is used as a bronchodilator[1].

Name	4-[2-[1-(1,3-benzodioxol-5-yl)propan-2-ylamino]-1-hydroxyethyl]benzene-1,2-diol
Synonym	More Synonyms

Description	Protokylol (Caytine; JB-251) is a beta-adrenergic receptor agonist and TRPV1 agonist. Protokylol is used as a bronchodilator[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
References	[1]. Corina Andrei, et al. In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity. Pharmaceutics. 2022 Nov 22;14(12):2563.

Density	1.336g/cm3
Boiling Point	585ºC at 760 mmHg
Molecular Formula	C₁₈H₂₁NO₅
Molecular Weight	331.36300
Flash Point	307.6ºC
Exact Mass	331.14200
PSA	91.18000
LogP	2.47160
Vapour Pressure	1.57E-14mmHg at 25°C
Index of Refraction	1.638
InChIKey	LUMAEVHDZXIGEP-UHFFFAOYSA-N
SMILES	CC(Cc1ccc2c(c1)OCO2)NCC(O)c1ccc(O)c(O)c1

Name: insulin secretion from INS-1E cells in the presence of 5 mM glucose-screen
Source: 846
Target: N/A
External Id: 5mMGluc_INS1E_InsulinRelease_40mMGluc_SP

Name: Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu...
Source: NCGC
External Id: CYP3A4437

Name: Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2D6395

Name: GSK3B-pretreated HCT116 viability from Cell TiterGlo-screen
Source: 846
Target: N/A
External Id: GSK3b_inh_pretreated_Viability_ATP_HCT116_SP

Name: Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2C9536

Name: Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Source: NCGC
Target: N/A
External Id: TRND-SARS-CoV-2-cytotox-48hr

Name: Displacement of (-)-[3H]alprenolol from adrenergic receptor purified from frog erythr...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3253168

Name: GLP1 secretion from NCI-H716 cells-screen
Source: 846
Target: N/A
External Id: hNCI-H716_GLP1_Secretion_SP

Name: Displacement of (-)-[3H]alprenolol from adrenergic receptor purified from frog erythr...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3253167

Name: VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-screen
Source: 846
Target: N/A
External Id: VEGF_ADSC_ECFC_Angio_CD31_TubeArea_SP

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EINECS 205-255-3

JB 251

protokylol

AN 1031

Beres

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Protokylol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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Protokylol

Use of Protokylol

Names

Protokylol Biological Activity

Chemical & Physical Properties

ProtokylolBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.