LabMol-301

Modify Date: 2024-04-06 16:21:50

LabMol-301 Structure
LabMol-301 structure
Common Name LabMol-301
CAS Number 1360243-08-8 Molecular Weight 316.36
Density N/A Boiling Point N/A
Molecular Formula C18H16N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LabMol-301


LabMol-301 inhibits both NS5 RdRp and NS2B-NS3pro activity (IC50: 0.8 and 7.4 μM, respectively). LabMol-301 has a cytoprotective effect and prevents Zika virus (ZIKV)-induced cell death[1].

 Names

Name LabMol-301

 LabMol-301 Biological Activity

Description LabMol-301 inhibits both NS5 RdRp and NS2B-NS3pro activity (IC50: 0.8 and 7.4 μM, respectively). LabMol-301 has a cytoprotective effect and prevents Zika virus (ZIKV)-induced cell death[1].
Related Catalog
Target

NS5 RdRp, NS2B-NS3pro[1]

In Vitro LabMol-301 (20 μM) shows 99% inhibition rate of NS5 RdRp activity[1]. LabMol-301 (10 μM) inhibits more than 80% of the NS2B-NS3pro protease activity[1]. LabMol-301 interacts with ZIKV NS2B-NS3pro at the allosteric site relied on a highly hydrophobic complementarity between the molecule’s surfaces and the protein[1]. LabMol-301 is able to protect GSC387 cell from cell death induced by ZIKV (EC50: 6.68 μM)[1].

 Chemical & Physical Properties

Molecular Formula C18H16N6
Molecular Weight 316.36
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