N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide
Modify Date: 2024-04-06 12:35:52
N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide structure
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Common Name | N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide | ||
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| CAS Number | 1372407-07-2 | Molecular Weight | 568.59 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 712.2±60.0 °C at 760 mmHg | |
| Molecular Formula | C29H31F3N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 384.5±32.9 °C | |
Use of N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide(s)-PF-4136309 is the inactive isomer of PF-4136309 (HY-13245), and can be used as an experimental control. PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. |
| Name | Benzamide, N-[2-[(3S)-3-[[cis-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)- |
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| Synonym | More Synonyms |
| Description | (s)-PF-4136309 is the inactive isomer of PF-4136309 (HY-13245), and can be used as an experimental control. PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 712.2±60.0 °C at 760 mmHg |
| Molecular Formula | C29H31F3N6O3 |
| Molecular Weight | 568.59 |
| Flash Point | 384.5±32.9 °C |
| Exact Mass | 568.240967 |
| LogP | 2.10 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.626 |
| Benzamide, N-[2-[(3S)-3-[[trans-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)- |
| PF-4136309 |
| N-{2-[(3S)-3-({trans-4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide |
| MFCD22124474 |