Di-tert-butyl diisopropylphosphoramidoite

Modify Date: 2024-01-09 19:26:41

Di-tert-butyl diisopropylphosphoramidoite Structure
Di-tert-butyl diisopropylphosphoramidoite structure
Common Name Di-tert-butyl diisopropylphosphoramidoite
CAS Number 137348-86-8 Molecular Weight 277.39
Density 0.879 Boiling Point 252.2±9.0 °C at 760 mmHg
Molecular Formula C14H32NO2P Melting Point 85-90ºC 0.2 mm Hg(lit.)
MSDS Chinese USA Flash Point 106.4±18.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Di-tert-butyl diisopropylphosphoramidoite


Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

 Names

Name Di-tert-butyl N,N-diisopropylphosphoramidite
Synonym More Synonyms

  Biological Activity

Description Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
Related Catalog

 Chemical & Physical Properties

Density 0.879
Boiling Point 252.2±9.0 °C at 760 mmHg
Melting Point 85-90ºC 0.2 mm Hg(lit.)
Molecular Formula C14H32NO2P
Molecular Weight 277.39
Flash Point 106.4±18.7 °C
Exact Mass 277.217072
PSA 35.29000
LogP 5.72
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.444
Storage condition −20°C
Stability Moisture Sensitive

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~61%

Di-tert-butyl diisopropylphosphoramidoite Structure

Di-tert-butyl d...

CAS#:137348-86-8

Literature: US7018987 B1, ; Page/Page column 9 ;

~58%

Di-tert-butyl diisopropylphosphoramidoite Structure

Di-tert-butyl d...

CAS#:137348-86-8

Literature: Helvetica Chimica Acta, , vol. 74, # 6 p. 1314 - 1328

~%

Di-tert-butyl diisopropylphosphoramidoite Structure

Di-tert-butyl d...

CAS#:137348-86-8

Literature: Phosphorus, Sulfur and Silicon and Related Elements, , vol. 164, p. 277 - 291

 Synonyms

Di-tert-butyl N,N-DiisopropylphosphoraMidite
Di-tert-butyl diisopropylphosphoramidoite
Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(1,1-dimethylethyl) ester
Di-tert-butoxy(diisopropylamino)phosphine
MFCD00153506
Bis(2-methyl-2-propanyl) diisopropylphosphoramidoite
Di-tert-butyl diisopropylphosphoramidite
N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-propan-2-ylpropan-2-amine