TUG 891

Modify Date: 2024-01-02 19:30:02

TUG 891 Structure
TUG 891 structure
 Common Name TUG 891
CAS Number 1374516-07-0 Molecular Weight 364.40900
Density N/A Boiling Point N/A
Molecular Formula C23H21FO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TUG 891


TUG-891 is a potent and selective agonist of the long chain free fatty acid (LCFA) receptor 4.

 Names

Name 3-{4-[(4-Fluoro-4'-methyl-2-biphenylyl)methoxy]phenyl}propanoic a cid
Synonym More Synonyms

 TUG 891 Biological Activity

Description TUG-891 is a potent and selective agonist of the long chain free fatty acid (LCFA) receptor 4.
Related Catalog
In Vitro TUG-891 displays similar signaling properties to the LCFA α-linolenic acid at human FFA4, including stimulation of Ca2+ mobilization, β-arrestin-1 and β-arrestin-2 recruitment, and extracellular signal-regulated kinase phosphorylation. Activation of human FFA4 by TUG-891 also results in rapid phosphorylation and internalization of the receptor[1].
References

[1]. Hudson BD, et al. The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism. Mol Pharmacol. 2013 Nov;84(5):710-25.

 Chemical & Physical Properties

Molecular Formula C23H21FO3
Molecular Weight 364.40900
Exact Mass 364.14700
PSA 46.53000
LogP 5.39730
Storage condition 2-8℃

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

tug-770
TUG 891
TUG-891
TUG891
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Chemsrc provides TUG 891(CAS#:1374516-07-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TUG 891 are included as well.>> amp version: TUG 891

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