ent-Ezetimibe

Modify Date: 2024-01-04 11:54:17

ent-Ezetimibe structure	Common Name	ent-Ezetimibe
	CAS Number	1376614-99-1	Molecular Weight	409.42500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₁F₂NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ent-Ezetimibe

ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator[1].

Name	ezetimibe
Synonym	More Synonyms

Description	ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator[1].
Related Catalog	Research Areas >> Cardiovascular Disease
References	[1]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532. [2]. Yijun Zhu, et al. Efficient and scalable process for the synthesis of antihypercholesterolemic drug ezetimibe. An International Journal for Rapid Communication of Synthetic Organic Chemistry

Description

Related Catalog

Research Areas >> Cardiovascular Disease

References

[1]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.

[2]. Yijun Zhu, et al. Efficient and scalable process for the synthesis of antihypercholesterolemic drug ezetimibe. An International Journal for Rapid Communication of Synthetic Organic Chemistry