2,3-Bis(3-indolylmethyl)indole

Modify Date: 2025-08-20 18:59:38

2,3-Bis(3-indolylmethyl)indole Structure
2,3-Bis(3-indolylmethyl)indole structure
Common Name 2,3-Bis(3-indolylmethyl)indole
CAS Number 138250-72-3 Molecular Weight 375.47
Density 1.314g/cm3 Boiling Point 682.1ºC at 760mmHg
Molecular Formula C26H21N3 Melting Point N/A
MSDS N/A Flash Point 306.6ºC

 Use of 2,3-Bis(3-indolylmethyl)indole


2,3-Bis(3-indolylmethyl)indole significantly suppresses RANKL-induced osteoclast formation, actin ring formation, and bone resorption in a concentration-dependent manner.

 Names

Name 2,3-bis(1H-indol-3-ylmethyl)-1H-indole
Synonym More Synonyms

 2,3-Bis(3-indolylmethyl)indole Biological Activity

Description 2,3-Bis(3-indolylmethyl)indole significantly suppresses RANKL-induced osteoclast formation, actin ring formation, and bone resorption in a concentration-dependent manner.
Related Catalog
References

[1]. Ha MT, et al. Anti-osteoclastogenic Effects of Indole Alkaloids Isolated from Barley (Hordeum vulgare Var. Hexastichon) Grass. J Agric Food Chem. 2021 Nov 10;69(44):12994-13005.

 Chemical & Physical Properties

Density 1.314g/cm3
Boiling Point 682.1ºC at 760mmHg
Molecular Formula C26H21N3
Molecular Weight 375.47
Flash Point 306.6ºC
Exact Mass 375.17400
PSA 47.37000
LogP 6.31210
Vapour Pressure 1.09E-17mmHg at 25°C
Index of Refraction 1.796
InChIKey MJHVZTDHBWQIMN-UHFFFAOYSA-N
SMILES c1ccc2c(Cc3[nH]c4ccccc4c3Cc3c[nH]c4ccccc34)c[nH]c2c1

 Synonyms

1H-Indole,2,3-bis(1H-indol-3-ylmethyl)
2-(indol-3-ylmethyl)-3,3'-diindolylmethane
Bisimi
2,3-diskatylindole
3,3'-indole-2,3-diyldimethyl-bis-indole
2-(indol-3-ylmethyl)-3,3'-methylenediindole
2,3-Bis(3-indolylmethyl)indole
3,3'-(1H-indole-2,3-diyl)bis(methylene)bis(1H-indole)
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