marmesin

Modify Date: 2024-01-02 18:58:50

marmesin Structure
marmesin structure
Common Name marmesin
CAS Number 13849-08-6 Molecular Weight 246.259
Density 1.3±0.1 g/cm3 Boiling Point 434.0±45.0 °C at 760 mmHg
Molecular Formula C14H14O4 Melting Point 189-191℃
MSDS N/A Flash Point 168.0±22.2 °C

 Use of marmesin


S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

 Names

Name (+)-marmesin
Synonym More Synonyms

 marmesin Biological Activity

Description S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.
Related Catalog
Target

COX-2

5-Lipoxygenase

In Vitro S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism[1]. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity[2].
References

[1]. Larbat R, et al. Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis. J Biol Chem. 2007 Jan 5;282(1):542-54. Epub 2006 Oct 26.

[2]. Kim JS, et al. Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res. 2006 Aug;29(8):617-23.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 434.0±45.0 °C at 760 mmHg
Melting Point 189-191℃
Molecular Formula C14H14O4
Molecular Weight 246.259
Flash Point 168.0±22.2 °C
Exact Mass 246.089203
PSA 59.67000
LogP 1.69
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.611
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LV1045500
CHEMICAL NAME :
7H-Furo(3,2-g)(1)benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-(+)-
CAS REGISTRY NUMBER :
13849-08-6
LAST UPDATED :
199410
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H14-O4
MOLECULAR WEIGHT :
246.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
1040 ng/plate
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 13,521,1984

 Synonyms

2-(2-Hydroxy-2-propanyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one
2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one
(7S)-marmesin
marmesin
2-(2-hydroxypropan-2-yl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one
7H-Furo[3,2-g][1]benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-
2-(1-Hydroxy-1-methyl-ethyl)-2,3-dihydro-furo[3,2-g]chromen-7-one
S(+)-Marmesin
2-(1-Hydroxy-1-methylethyl)-2,3-dihydrofuro[3,2-g]chromen-7-one
(2S)-2-(2-hydroxypropan-2-yl)-2,3-dihydrofuro[3,2-g]chromen-7-one
S-(+)-Marmesin
Top Suppliers:I want be here

  • DC Chemicals Limited
  • China
  • Product Name: Marmesin
  • Price: $700.0/100mg $1200.0/250mg $2500.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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Price: $163/10mM*1mLinDMSO

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