2-(2-Boc-aminoethoxy)ethanol

Modify Date: 2024-01-02 16:59:00

2-(2-Boc-aminoethoxy)ethanol Structure
2-(2-Boc-aminoethoxy)ethanol structure
Common Name 2-(2-Boc-aminoethoxy)ethanol
CAS Number 139115-91-6 Molecular Weight 205.251
Density 1.061 g/mL at 25 °C Boiling Point 332.9±22.0 °C at 760 mmHg
Molecular Formula C9H19NO4 Melting Point N/A
MSDS Chinese USA Flash Point 155.1±22.3 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of 2-(2-Boc-aminoethoxy)ethanol


PROTAC Linker 11 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 11 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name tert-butyl N-[2-(2-hydroxyethoxy)ethyl]carbamate
Synonym More Synonyms

 2-(2-Boc-aminoethoxy)ethanol Biological Activity

Description PROTAC Linker 11 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 11 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.061 g/mL at 25 °C
Boiling Point 332.9±22.0 °C at 760 mmHg
Molecular Formula C9H19NO4
Molecular Weight 205.251
Flash Point 155.1±22.3 °C
Exact Mass 205.131409
PSA 67.79000
LogP 0.41
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.454
Storage condition 2-8°C

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319
Precautionary Statements P301 + P310-P305 + P351 + P338
Hazard Codes T
Risk Phrases 25-36-37-38
Safety Phrases 36/39-45
RIDADR 2810
WGK Germany 3
Packaging Group
Hazard Class 6.1
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2-(2-N-Boc-aminoethoxy)ethanol
tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate
2-(N-Boc-2-aminoethoxy)ethanol
2,7-BIS(TERT-BUTYLDIMETHYLSILANYLOXY)NAPHTHALENE
Carbamic acid, N-[2-(2-hydroxyethoxy)ethyl]-, 1,1-dimethylethyl ester
[2-(2-Hydroxy-ethoxy)-ethyl]-carbamic acid tert-butyl ester
2-(2-Boc-aminoethoxy)ethanol
Boc-2-(2-aminoethoxy)ethanol
N-Boc-2-(2-hydroxyethoxy)-ethylamine
2-(2-tert-butyloxycarbonylaminoethoxy)ethanol
2-Methyl-2-propanyl [2-(2-hydroxyethoxy)ethyl]carbamate
AmbotzPEG1020
2-[2-(Boc-amino)ethoxy]ethanol
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