(2S)-Octyl-α-hydroxyglutarate

Modify Date: 2024-01-10 17:17:34

(2S)-Octyl-α-hydroxyglutarate Structure
(2S)-Octyl-α-hydroxyglutarate structure
Common Name (2S)-Octyl-α-hydroxyglutarate
CAS Number 1391194-64-1 Molecular Weight 260.327
Density 1.1±0.1 g/cm3 Boiling Point 420.5±35.0 °C at 760 mmHg
Molecular Formula C13H24O5 Melting Point N/A
MSDS N/A Flash Point 152.3±19.4 °C

 Use of (2S)-Octyl-α-hydroxyglutarate


(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.

 Names

Name (2S)-Octyl-α-hydroxyglutarate
Synonym More Synonyms

 (2S)-Octyl-α-hydroxyglutarate Biological Activity

Description (2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.
Related Catalog
In Vitro Treatment of IDH1-WT HeLa cells with (2S)-Octyl-α-hydroxyglutarate, a modified form of 2-Hydroxyglutarate with high cellular uptake, results in a dose-dependent increase in DSBs in log-phase cells[1].
References

[1]. Sulkowski PL, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologousrecombination and induces PARP inhibitor sensitivity. Sci Transl Med. 2017 Feb 1;9(375).

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 420.5±35.0 °C at 760 mmHg
Molecular Formula C13H24O5
Molecular Weight 260.327
Flash Point 152.3±19.4 °C
Exact Mass 260.162384
LogP 3.03
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.473

 Synonyms

Pentanedioic acid, 2-hydroxy-, 1-octyl ester, (2S)-
(4S)-4-Hydroxy-5-(octyloxy)-5-oxopentanoic acid
MFCD29045545
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