Kitasamycin

Modify Date: 2024-01-03 09:52:18

Kitasamycin structure	Common Name	Kitasamycin
	CAS Number	1392-21-8	Molecular Weight	785.958
	Density	1.2±0.1 g/cm3	Boiling Point	874.7±65.0 °C at 760 mmHg
	Molecular Formula	C₄₀H₆₇NO₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	482.8±34.3 °C

Use of Kitasamycin

Leucomycin (kitasamycin) is a macrolide antibiotic produced by Streptomyces kitasatoensis[1][2][3][4].

Name	Kitasamycin
Synonym	More Synonyms

Description	Leucomycin (kitasamycin) is a macrolide antibiotic produced by Streptomyces kitasatoensis[1][2][3][4].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. PACHTMAN EA, et al. Leucomycin; a new antibiotic. Am J Pharm Sci Support Public Health. 1958 Oct;130(10):342-4. [2]. Vézina C, et al. Biosynthesis of kitasamycin (leucomycin) by leucine analog-resistant mutants of Streptomyces kitasatoensis. Antimicrob Agents Chemother. 1979 May;15(5):738-46. [3]. La T, et al. Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs. Aust Vet J. 2019 Sep 17. [4]. Hassan AB, et al. Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers. Dtsch Tierarztl Wochenschr. 1990 Aug;97(8):315-7.

Description

Leucomycin (kitasamycin) is a macrolide antibiotic produced by Streptomyces kitasatoensis[1][2][3][4].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. PACHTMAN EA, et al. Leucomycin; a new antibiotic. Am J Pharm Sci Support Public Health. 1958 Oct;130(10):342-4.

[2]. Vézina C, et al. Biosynthesis of kitasamycin (leucomycin) by leucine analog-resistant mutants of Streptomyces kitasatoensis. Antimicrob Agents Chemother. 1979 May;15(5):738-46.

[3]. La T, et al. Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs. Aust Vet J. 2019 Sep 17.

[4]. Hassan AB, et al. Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers. Dtsch Tierarztl Wochenschr. 1990 Aug;97(8):315-7.

Density	1.2±0.1 g/cm3
Boiling Point	874.7±65.0 °C at 760 mmHg
Molecular Formula	C₄₀H₆₇NO₁₄
Molecular Weight	785.958
Flash Point	482.8±34.3 °C
Exact Mass	785.456177
LogP	3.35
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.541
Storage condition	2-8°C
Water Solubility	ethanol: 50 mg/mL, clear to slightly hazy, light-yellow

Hazard Codes	Xi
Safety Phrases	24/25
WGK Germany	1
RTECS	WG9400000

(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-Dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (non-preferred name)

Ayermycin

3-Deacetyljosamycin

Sineptina

Syneptine

EINECS 232-429-6

3-O-Deacetyljosamycin

Kitasamycin

Leucomycin A1

Stereomycine