Zolmitriptan

Modify Date: 2024-01-02 16:36:54

Zolmitriptan Structure
Zolmitriptan structure
Common Name Zolmitriptan
CAS Number 139264-17-8 Molecular Weight 287.357
Density 1.2±0.1 g/cm3 Boiling Point 563.3±38.0 °C at 760 mmHg
Molecular Formula C16H21N3O2 Melting Point 136-141ºC
MSDS Chinese USA Flash Point 294.5±26.8 °C

 Names

Name zolmitriptan
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 563.3±38.0 °C at 760 mmHg
Melting Point 136-141ºC
Molecular Formula C16H21N3O2
Molecular Weight 287.357
Flash Point 294.5±26.8 °C
Exact Mass 287.163391
PSA 57.36000
LogP 1.64
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.620
Storage condition Refrigerator

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
RTECS RQ2707000
HS Code 2934999090

 Synthetic Route

~87%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: LABORATORIOS VITA, S. A. Patent: WO2004/14901 A1, 2004 ; Location in patent: Page 18-19 ;

~%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: WO2009/44211 A1, ; Page/Page column 17; 22-23 ;

~74%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: Aminul, Islam; Chandan, Bhar; Sahadev, Katam Patent: US2005/245585 A1, 2005 ; Location in patent: Page/Page column title page; 9-10; Figure 1 ;

~74%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: Aminul, Islam; Chandan, Bhar; Sahadev, Katam Patent: US2005/245585 A1, 2005 ; Location in patent: Page/Page column 8 ;

~46%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: Aminul, Islam; Chandan, Bhar; Sahadev, Katam Patent: US2005/245585 A1, 2005 ; Location in patent: Page/Page column 8-9 ;

~%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: WO2008/104134 A2, ; Page/Page column title page; 5-7 ;

~%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: WO2008/104135 A1, ; Page/Page column 5 ;

~%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: US2011/112157 A1, ;

~%

Zolmitriptan Structure

Zolmitriptan

CAS#:139264-17-8

Literature: WO2008/104135 A1, ; Page/Page column 4 ;

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles47

More Articles
Bioenhanced sublingual tablet of drug with limited permeability using novel surfactant binder and microencapsulated polysorbate: In vitro/in vivo evaluation.

Eur. J. Pharm. Biopharm. 94 , 386-92, (2015)

Formulation of sublingual tablets of drugs with limited permeability poses a great challenge due to their poor absorption. In this study, bioenhanced sublingual tablets (BESTs) of zolmitriptan were pr...

Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.

PLoS ONE 8(1) , e52683, (2013)

Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol. Here we analyzed the effects of zolmitriptan on portal pressure ...

Preparation and evaluation of zolmitriptan submicron emulsion for rapid and effective nasal absorption in beagle dogs.

Drug Dev. Ind. Pharm. 37(12) , 1509-16, (2011)

Submicron emulsion was prepared for rapid and effective nasal absorption of zolmitriptan (ZT). The different charge inducers and pH values of the formulations were evaluated to optimize the formulatio...

 Synonyms

2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (4S)-
BW 311C90
(S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone
Zomigoro
(4S)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
Zolmitriptan
Zomigon
(4R)-4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one
(S)-N,N-Dimethyl-2-[5-(2-oxo-1,3-oxazolidin-4-ylmethyl)-1H-indol-3-yl]ethylamine
AscoTop
Zomig
MFCD00871503
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