Buddlejasaponin IV

Modify Date: 2024-01-10 18:37:17

Buddlejasaponin IV Structure
Buddlejasaponin IV structure
Common Name Buddlejasaponin IV
CAS Number 139523-30-1 Molecular Weight 943.12200
Density 1.43g/cm3 Boiling Point N/A
Molecular Formula C48H78O18 Melting Point 288-290 ºC
MSDS N/A Flash Point N/A

 Use of Buddlejasaponin IV


Buddlejasaponin IV (BS‐IV) exerts anti-inflammatory and cytotoxic effects against cancer cells[1].

 Names

Name Buddlejasaponin IV
Synonym More Synonyms

 Buddlejasaponin IV Biological Activity

Description Buddlejasaponin IV (BS‐IV) exerts anti-inflammatory and cytotoxic effects against cancer cells[1].
Related Catalog
In Vitro Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes[1]. Buddlejasaponin IV (BS-IV) exhibits anti-inflammatory effect of through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-κB inactivation[2].
References

[1]. Young Sun Hwang, et al. Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes. Phytother Res. 2011 Oct;25(10):1503-10.

[2]. Jong-Heon Won, et al. Anti-inflammatory effect of buddlejasaponin IV through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-kappaB inactivation. Br J Pharmacol. 2006 May;148(2):216-25.

 Chemical & Physical Properties

Density 1.43g/cm3
Melting Point 288-290 ºC
Molecular Formula C48H78O18
Molecular Weight 943.12200
Exact Mass 942.51900
PSA 287.14000
Index of Refraction 1.632
Water Solubility Practically insoluble (0.017 g/L) (25 ºC)

 Synonyms

y0043
Buddleoglucoside IV
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