6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone HCl
Modify Date: 2025-09-15 13:54:01
6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone HCl structure
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Common Name | 6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone HCl | ||
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| CAS Number | 139652-86-1 | Molecular Weight | 472.01600 | |
| Density | N/A | Boiling Point | 615.5ºC at 760 mmHg | |
| Molecular Formula | C27H34ClNO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 326.1ºC | |
Use of 6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone HClSigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a Ki of 4000 nM at the dopamine D2 receptor[1]. |
| Name | 6-[6-(4-hydroxypiperidin-1-yl)hexoxy]-3-methyl-2-phenylchromen-4-one,hydrochloride |
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| Synonym | More Synonyms |
| Description | Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a Ki of 4000 nM at the dopamine D2 receptor[1]. |
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| Related Catalog | |
| Target |
IC50: 16 nM (DTG site of sigma receptor), 19 nM (PPP site of sigma receptor)[1] Ki: 4000 nM (Dopamine D2 receptor)[1] |
| In Vivo | Administration of Sigma-LIGAND-1 hydrochloride reverseS amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds. Sigma-LIGAND-1 hydrochloride and its structural analogues have the potential antipsychotic activity[1]. |
| References |
| Boiling Point | 615.5ºC at 760 mmHg |
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| Molecular Formula | C27H34ClNO4 |
| Molecular Weight | 472.01600 |
| Flash Point | 326.1ºC |
| Exact Mass | 471.21800 |
| PSA | 62.91000 |
| LogP | 5.90420 |
| Vapour Pressure | 5.23E-16mmHg at 25°C |
| InChIKey | GWSBQIZSTCDSLE-UHFFFAOYSA-N |
| SMILES | Cc1c(-c2ccccc2)oc2ccc(OCCCCCCN3CCC(O)CC3)cc2c1=O.Cl |
| 6-[6-(4-Hydroxypiperidinyl)hexoxy]-3-methyl-2-phenyl-4H-1-benzopyran-4-one hydrochloride |
| 6-(6-(4-Hydroxypiperidinyl)hexyloxy)-3-methylflavone HCl |
| 4H-1-Benzopyran-4-one,6-((6-(4-hydroxy-1-piperidinyl)hexyl)oxy)-3-methyl-2-phenyl-,hydrochloride |
| 6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone hydrochloride |