LAS191954
Modify Date: 2025-09-22 13:08:34
LAS191954 structure
|
Common Name | LAS191954 | ||
|---|---|---|---|---|
| CAS Number | 1403947-26-1 | Molecular Weight | 397.393 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 769.0±70.0 °C at 760 mmHg | |
| Molecular Formula | C20H15N9O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 418.9±35.7 °C | |
Use of LAS191954LAS191954 is a potent, selective and orally active PI3Kδ inhibitor for inflammatory diseases treatment, with an IC50 of 2.6 nM[1]. |
| Name | 2-{(1S)-1-[(6-Amino-5-cyano-4-pyrimidinyl)amino]ethyl}-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-5-carbonitrile |
|---|---|
| Synonym | More Synonyms |
| Description | LAS191954 is a potent, selective and orally active PI3Kδ inhibitor for inflammatory diseases treatment, with an IC50 of 2.6 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
PI3Kδ:2.6 nM (IC50) |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 769.0±70.0 °C at 760 mmHg |
| Molecular Formula | C20H15N9O |
| Molecular Weight | 397.393 |
| Flash Point | 418.9±35.7 °C |
| Exact Mass | 397.139954 |
| LogP | 1.11 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.769 |
| 2-{(1S)-1-[(6-Amino-5-cyano-4-pyrimidinyl)amino]ethyl}-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-5-carbonitrile |
| Pyrrolo[2,1-f][1,2,4]triazine-5-carbonitrile, 2-[(1S)-1-[(6-amino-5-cyano-4-pyrimidinyl)amino]ethyl]-3,4-dihydro-4-oxo-3-phenyl- |
| MFCD28502110 |