2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine

Modify Date: 2024-01-20 18:13:52

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure
2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine structure
Common Name 2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine
CAS Number 14097-40-6 Molecular Weight 162.23200
Density 1.084g/cm3 Boiling Point 290.805ºC at 760 mmHg
Molecular Formula C10H14N2 Melting Point N/A
MSDS N/A Flash Point 113.132ºC

 Names

Name 2-methyl-3,4-dihydro-1H-isoquinolin-7-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.084g/cm3
Boiling Point 290.805ºC at 760 mmHg
Molecular Formula C10H14N2
Molecular Weight 162.23200
Flash Point 113.132ºC
Exact Mass 162.11600
PSA 29.26000
LogP 1.77580
Vapour Pressure 0.002mmHg at 25°C
Index of Refraction 1.597

 Synthetic Route

~98%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

~97%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2007/48802 A1, 2007 ; Location in patent: Page/Page column 93 ;

~%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

~%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

~%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

~%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: ABBOTT LABORATORIES; BA-MAUNG, Nwe Y.; CLARK, Richard F.; ERICKSON, Scott A.; FIDANZE, Steve D.; KAWAI, Megumi; MANTEI, Robert A.; SHEPPARD, George S.; SORENSON, Bryan K.; WANG, Gary T. Patent: WO2011/53476 A1, 2011 ; WO 2011/053476 A1

~%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; COOK, Brian Nicholas; KOWALSKI, Jennifer A.; LI, Xiang; MARSHALL, Daniel Richard; SCHLYER, Sabine; SIBLEY, Robert; SMITH-KEENAN, Lana Louise; SOLEYMANZADEH, Fariba; SORCEK, Ronald John; YOUNG, Erick Richard Roush; ZHANG, Yunlong Patent: WO2012/6203 A1, 2012 ; WO 2012/006203 A1

~%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: Ochiai; Nakagome Chemical and Pharmaceutical Bulletin, 1958 , vol. 6, p. 497,500

~%

2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine Structure

2-methyl-1,2,3,...

CAS#:14097-40-6

Literature: Lusinchi et al. Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1959 , vol. 248, p. 426

 Synonyms

1,2,3,4-TETRAHYDRO-2-METHYL-7-ISOQUINOLINAMINE
2-methyl-7-amino-1,2,3,4-tetrahydroisoquinoline
7-Isoquinolinamine,1,2,3,4-tetrahydro-2-methyl
7-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline
2-methyl-1,2,3,4-tetrahydro-7-isoquinolinamine
2-METHYL-1,2,3,4-TETRAHYDROISOQUINOLIN-7-AMINE