(R)-PS210
Modify Date: 2025-12-28 10:34:00
(R)-PS210 structure
|
Common Name | (R)-PS210 | ||
|---|---|---|---|---|
| CAS Number | 1410101-89-1 | Molecular Weight | 380.31 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H15F3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (R)-PS210(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment[1]. |
| Name | (R)-PS210 |
|---|
| Description | (R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment[1]. |
|---|---|
| Related Catalog | |
| Target |
AC50: 1.8 μM (PDK1)[1] |
| In Vitro | (R)-PS210 displays an AC50 value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay. And the maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold[1]. |
| References |
| Molecular Formula | C19H15F3O5 |
|---|---|
| Molecular Weight | 380.31 |
|
Name: Activation of PDK1 using KTFCGTPEYLAPEVRR as substrate and [gamma32P]-ATP/Mg2+ by pho...
Source: ChEMBL
Target: 3-phosphoinositide-dependent protein kinase 1
External Id: CHEMBL2182501
|
|
Name: Activation of PDK1 assessed as half maximal activation using KTFCGTPEYLAPEVRR as subs...
Source: ChEMBL
Target: 3-phosphoinositide-dependent protein kinase 1
External Id: CHEMBL2182500
|
Total 2, Current Page 1 of 1
1