albomycin

Modify Date: 2025-08-25 14:20:47

albomycin Structure
albomycin structure
Common Name albomycin
CAS Number 1414-39-7 Molecular Weight 1006.81000
Density N/A Boiling Point N/A
Molecular Formula C36H58FeN10O18S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of albomycin


Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer[1].

 Names

Name albomycin δ1
Synonym More Synonyms

 albomycin Biological Activity

Description Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer[1].
Related Catalog
In Vitro Albomycin 也与 FhuA 结合,与高铁色素竞争结合位点。FhuA 是埋在大肠杆菌外膜的 β 桶。或者,Albomycin 结合 FhuD,FhuD 是细胞膜 ABC 转运蛋白 FhuB/FhuC 的质周亚基[1]。 Albomycin 对肺炎链球菌的生长有明显的抑制作用,最低抑制浓度为 4-62 nM[1]。
References

[1]. Travin DY, et al. Natural Trojan horse inhibitors of aminoacyl-tRNA synthetases. RSC Chem Biol. 2021 Feb 22;2(2):468-485.  

 Chemical & Physical Properties

Molecular Formula C36H58FeN10O18S
Molecular Weight 1006.81000
Exact Mass 1006.30000
PSA 465.52000

 Synonyms

ferric 2-[[2-[[5-(acetyl-hydroxy-amino)-2-[[5-(acetyl-hydroxy-ami no)-2-[[5-(acetyl-hydroxy-amino)-2-amino-pentanoyl]amino]pentanoy l]amino]pentanoyl]amino]-3-hydroxy-propanoyl]amino]-3-[(2R,3S,4R, 5R)-3,4-dihydroxy-5-(3-methyl-2,4-dioxo
albomycin delta1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.