TL-895
Modify Date: 2024-04-05 17:55:31
TL-895 structure
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Common Name | TL-895 | ||
|---|---|---|---|---|
| CAS Number | 1415823-49-2 | Molecular Weight | 447.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H26FN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TL-895TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC50 and a Ki of 1.5 nM and 11.9 nM, respectively[1]. TL-895 is used be for JAKi-relapsed/refractory myelofibrosis, acute myeloid leukemia, COVID-19 and cancer research[2][3][4]. |
| Name | TL-895 |
|---|
| Description | TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC50 and a Ki of 1.5 nM and 11.9 nM, respectively[1]. TL-895 is used be for JAKi-relapsed/refractory myelofibrosis, acute myeloid leukemia, COVID-19 and cancer research[2][3][4]. |
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| Related Catalog | |
| Target |
IC50: 1.5 nM; Ki: 11.9 nM (BTK)[1] |
| References |
| Molecular Formula | C25H26FN5O2 |
|---|---|
| Molecular Weight | 447.50 |